| 人脂联素蛋白与血管功能调控 |
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| 引用本文： | 封淑颖,邹竹荣.人脂联素蛋白与血管功能调控[J].生命科学,2006,18(5):497-501. |
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| 作者姓名： | 封淑颖 邹竹荣 |
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| 作者单位： | 华东师范大学生命科学学院,上海,200062 |
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| 基金项目： | 国家自然科学基金(3047022) |
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| 摘 要： | 当前,越来越多的研究聚焦于由脂肪组织分泌产生的血浆蛋白,即脂肪细胞因子对血管的直接作用,其中最引人注目的是脂联素表现出显著的抗炎症和抗动脉粥样硬化的功效。本综述主要总结了脂联素对血管功能影响的研究进展,并从几方面,诸如对血管结构、内皮细胞炎症反应、一氧化氮(NO)产生及血管生成的影响进行详细阐述。
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| 关 键 词： | 脂联素 内皮细胞 血管功能 |
| 文章编号： | 1004-0374（2006）05-0497-05 |
| 收稿时间： | 2006-01-22 |
| 修稿时间： | 2006-02-15 |
Human adiponectin and vascular function regulating |
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| FENG Shu-Ying,ZOU Zhu-Rong.Human adiponectin and vascular function regulating[J].Chinese Bulletin of Life Sciences,2006,18(5):497-501. |
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| Authors: | FENG Shu-Ying ZOU Zhu-Rong |
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| Institution: | School of Life Sciences, East China Normal University, Shanghai 200062, China |
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| Abstract: | Nowadays, increasing studies have been focused on the direct vascular effects of some plasma proteins, termed adipokines that are secreted from adipose tissues. Therein, adiponectin predominantly exhib- its significant anti-inflammatory and anti-atherosclerotic effects. This brief review will summarize the recent work on the role of adiponectin in modulating the vascular functions, including the influences on the vascular structure, inflammatory responses of endothelium cells, nitric oxide (NO) generation and angiogenesis. |
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| Keywords: | adiponectin endothelial cells vascular function |
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