Induction of Hepatitis B Antibody in Experimental Animals by Immunization with A-2 Plaque Virus |
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| Authors: | E. D. Shaw A. P. McKee M. Rancourt L. Hollenbeck |
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| Affiliation: | Virology Division, Ortho Research Foundation, Raritan, New Jersey 08869 |
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| Abstract: | A sero-conversion for hepatitis B antibody has resulted from immunization of patas monkeys, guinea pigs, and rabbits with the A-2 plaque virus. This agent was isolated in tissue culture from patient sera that were positive for hepatitis B antigen. The immune response was assayed with techniques of direct and indirect counter-immunoelectrophoresis, and immune electron microscopy. |
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