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Studies with Brugia pahangi. 18. Anthelmintic effects of stibocaptate.
Authors:D A Denham  R R Suswillo  R Rogers
Abstract:Stibocaptate (Asiban, Hoffman--La Roche) killed third stage larvae of Brugia pahangi in vitro at 50 p.p.m. but had no effect on microfilariae at 1 X 10(4) p.p.m No larvae developed in infected mosquitoes fed 1% stibocaptate in 10% sucrose. It was neither micro-nor macrofilaricidal in either jirds or cats but did affect embryogenesis.
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