|
|||||
|
|
Stereoselective reduction of ketones by <Emphasis Type="Italic">Daucus carota</Emphasis> hairy root cultures |
|
| Authors: | Dave?Caron Andrew?P?Coughlan Mathieu?Simard Jonathan?Bernier Yves?Piché |
| Institution: | (1) Département de chimie, Faculté des sciences et de génie, CREFSIP, Université Laval, G1K 7P4 Québec , QC, Canada;(2) Département des sciences du bois et de la forêt, Centre de recherche en biologie forestière, Faculté de foresterie et de géomatique, Université Laval, G1K 7P4 Québec , QC, Canada |
| Abstract: | Reduction of acetophenone by Daucus carota hairy root cultures afforded (S)-phenylethanol in high yield (96%) and excellent enantiomeric excess (ee ≥ 98%). Aromatic ketones, keto esters, and a simple aliphatic ketone were reduced with good stereoselectivity (ee = 62–98%) and moderate to high chemical yields (25–90%). |
| Keywords: | acetophenone Daucus carota hairy root culture (S)-phenylethanol stereoselective reduction |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |