Glycolipid patterns supported by human serum albumin for E. coli recognition |
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| Authors: | Zhang Xiaoming He Qiang Yan Xuehai Boullanger Paul Li Junbai |
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| Affiliation: | Beijing National Lab for Molecular Sciences, Key Lab of Colloid and Interface Science, The Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Zhong Guan Cun, Bei Yi Jie 2, Beijing, China. |
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| Abstract: | We demonstrated that human serum albumin (HSA) patterns constructed in a solid substrate by using micro-contact printing (muCP) technique supported the deposition of phospholipid bilayer containing glycolipid, 10-tetradecyloxymethy-3,6,9,12-tetraoxahexacosyl 2-acetamido-2-deoxy-beta-D-glucopyranoside (PB1124). It is observed by confocal laser scanning microscopy (CLSM) that the obtained glycolipid patterns are well-defined, stable and can be used to recognize and immobilize Escherichia coli (E. coli). This strategy is promising to perform bacterial detection through solid surface recognition in a way of biosensors. |
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| Keywords: | Pattern E. coli Recognition Glycolipid HSA |
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