Cell-autonomous immunity to Toxoplasma gondii in mouse and man |
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| Authors: | Könen-Waisman Stephanie Howard Jonathan C |
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| Affiliation: | Institute for Genetics, University of Cologne, Zülpicher Strasse 47, 50674 Cologne, Germany. |
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| Abstract: | The protozoan, Toxoplasma gondii, is a natural pathogen of mouse and a zoonosis of man. Immunity against the pathogen is largely mediated by interferon-stimulated cell-autonomous mechanisms that are strikingly different between man and mouse. There are many poorly understood host and pathogen variables that affect the outcome of infection. |
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