| 大鼠肝癌模型CBRH—3的建立及其生物学特性 |
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| 引用本文： | 强家模 叶红. 大鼠肝癌模型CBRH—3的建立及其生物学特性[J]. 动物学报, 1996, 42(2): 166-171 |
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| 作者姓名： | 强家模 叶红 |
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| 作者单位： | 中国科学院上海细胞生物学研究所!上海200031 |
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| 摘 要： | 用ＤＥＮＡ诱发近交系Ｗｉｓｔａｒ大鼠，经三个月后得原发性肝癌，移植于同品系幼鼠，从而建立了 一株染色体众数正常，ＡＥＰ阳性的大鼠移植性肝癌模型，命名为ＣＢＲＨ－３，病理鉴定为肝细胞型肝 癌。至今已传至６０余代，目前生长稳定。
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| 关 键 词： | 肝癌 动物模型 大鼠 生物学特性 |
THE ESTABLISHMENT OF RAT HEPATOMA MODEL AND IT' S BIOLOGICAL CHARACTERS |
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| QIANG JIA-MO,YE HONG,XIE HONG. THE ESTABLISHMENT OF RAT HEPATOMA MODEL AND IT' S BIOLOGICAL CHARACTERS[J]. Acta Zoologica Sinica, 1996, 42(2): 166-171 |
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| Authors: | QIANG JIA-MO YE HONG XIE HONG |
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| Abstract: | Primary hepatomas were induced in Wistar rats by treatment with Diethylnitrosamine (DENA) for 3 months. From them a transplantable hepatoma with normal chromosome number, designated CBRH-3, was established in the same rat strain. Pathological examination shows that it is hepatocellular carcinoma. Up to now the transplantable rat hepatoma shows a steady growth rate and has been serially passed for more than 60 generations. |
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| Keywords: | Rat Hepatpcellular carcinoma Hepatoma model Chromosome. |
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