Construction and characterization of Escherichia coli disruptants defective in the yaeM gene. |
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| Authors: | T Kuzuyama S Takahashi H Seto |
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| Institution: | Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan. |
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| Abstract: | Escherichia coli disruptants defective in the yaeM gene, which is located at 4.2 min on the chromosome map, were constructed and characterized. The disruptants showed auxotrophy for 2-C-methylerythritol, a free alcohol of 2-C-methyl-D-erythritol 4-phosphate that is a biosynthetic precursor in the nonmevalonate pathway. This result clearly shows that the yaeM gene is indeed involved in this pathway in E. coli. |
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