PDZBase: a protein-protein interaction database for PDZ-domains |
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Authors: | Beuming Thijs Skrabanek Lucy Niv Masha Y Mukherjee Piali Weinstein Harel |
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Institution: | Department of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Ave., New York, NY 10021, USA. |
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Abstract: | SUMMARY: PDZBase is a database that aims to contain all known PDZ-domain-mediated protein-protein interactions. Currently, PDZBase contains approximately 300 such interactions, which have been manually extracted from > 200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through alignments (for the comparison of several interactions), or as residue-based diagrams including schematic secondary structure information (for individual complexes). |
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