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Molecular Characterization of Cryptosporidium spp. among Children in Rural Ghana
Authors:Daniel Eibach  Ralf Krumkamp  Hassan M. Al-Emran  Nimako Sarpong  Ralf Matthias Hagen  Yaw Adu-Sarkodie  Egbert Tannich  Jürgen May
Abstract:BackgroundThe relevance of Cryptosporidium infections for the burden of childhood diarrhoea in endemic settings has been shown in recent years. This study describes Cryptosporidium subtypes among symptomatic and asymptomatic children in rural Ghana to analyse subtype-specific demographic, geographical, seasonal and clinical differences in order to inform appropriate control measures in endemic areas.Conclusions/SignificanceCryptosporidiosis is characterized by seasonal anthroponotic transmission of strains typically found in Sub-Saharan Africa. The infection mainly affects young infants, with vomiting and diarrhoea being one of the leading symptoms in C. parvum infection. Combining molecular typing and clinical data provides valuable information for physicians and is able to track sources of infections.
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