Reading sequence-directed computational nucleosome maps |
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Authors: | Reshma Nibhani |
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Institution: | Institute of Evolution, University of Haifa, Haifa, Israel |
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Abstract: | Recently developed latest version of the sequence-directed single-base resolution nucleosome mapping reveals existence of strong nucleosomes and chromatin columnar structures (columns). Broad application of this simple technique for further studies of chromatin and chromosome structure requires some basic understanding as to how it works and what information it affords. The paper provides such an introduction to the method. The oscillating maps of singular nucleosomes, of short and long oligonucleosome columns, are explained, as well as maps of chromatin on satellite DNA and occurrences of counter-phase (antiparallel) nucleosome neighbors. |
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Keywords: | strong nucleosome columns alternative nucleosome positions chromatin structure chromosome structure |
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