Back to Units of Protein Folding |
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| Authors: | Igor N Berezovsky Edward N Trifonov |
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| Institution: | 1. Department of Structural Biology , The Weizmann Institute of Science , P.O.B. 26, Rehovot , 76100 , Israel;2. Genome Diversity Center , Institute of Evolution University of Haifa , Haifa , 31905 , Israel |
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| Abstract: | Abstract In response to the criticism by A. Finkelstein (J. Biomol. Struct. Dyn. 20, 311–314, 2002) of our Communication (J. Biomol. Struct. Dyn. 20, 5–6, 2002) several issues are dealt with. Importance of the notion of elementary folding unit, its size and structure, and the necessity of further characterization of the units for the elucidation of the protein folding in vivo are discussed. The criticism (J. Biomol. Struct. Dyn. 20, 311–314, 2002) on the hierarchical protein folding is also briefly addressed. |
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| Keywords: | Levinthal paradox folding units protein folding biological relevance |
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