Abstract: | Both eyes of anesthetized cynomolgus monkeys (Macaca fascicularis) were irradiated with 2.45-GHz microwaves, either pulsed or continuous wave. In vivo corneal endothelial abnormalities were observed by specular microscopy and confirmed through histologic techniques after a 16- to 48-hour postexposure period. Pulsed microwaves with an average power density of 10 mW/cm2 (equivalent to a specific absorption rate (SAR) = 2.6 W/kg) produced these effects, while levels of 20-30 mW/cm2 (equivalent to a SAR = 5.3 to 7.8 W/kg) with continuous wave irradiation were required to produce similar changes. |