Antibacterial and antifungal flavanones from Eysenhardtia texana |
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| Authors: | Wächter G A Hoffmann J J Furbacher T Blake M E Timmermann B N |
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| Institution: | Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson 85706, USA. |
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| Abstract: | An activity-guided fractionation of a methanol-dichloromethane extract obtained from the aerial parts of Eysenhardtia texana led to the isolation of two novel antibacterial and antifungal flavanones together with a known flavanone. Their structures were established as 4',5,7-trihydroxy-8-methyl-6-(3-methyl-2-butenyl])-(2S)-flavanone, 4',5,7-trihydroxy-6-methyl-8-(3-methyl-2-butenyl])-(2S)-flavanone and 4',5-dihydroxy-7-methoxy-6-(3-methyl-2-butenyl])-(2S)-flavanone on the basis of their UV, 1D and 2D-NMR spectra. |
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