The activities of peroxisomal oxidases in periportal and perivenous zones of the rat liver acinus |
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| Authors: | M Le Hir U C Dubach |
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| Institution: | (1) Departement für Innere Medizin, Kantonsspital, Medizinische Universitäts-Poliklinik, Petersgraben 4, CH-4031 Basel, Switzerland |
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| Abstract: | Summary Using a new biochemical microassay the activities of three peroxisomal oxidases in single microdissected periportal and perivenous zones of the liver acinus were measured. Whereas urate oxidase is homogeneously distributed through the acinus, the activities of D-aminoacid oxidase and  -hydroxyacid oxidase are respectively 1.80-and 2.71-fold higher in the periportal hepatocytes than in the perivenous hepatocytes. |
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