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Toward understanding the role of leptin and leptin receptor antagonism in preclinical models of rheumatoid arthritis
Authors:Otvos Laszlo  Shao Wen-Hai  Vanniasinghe Anne S  Amon Michael A  Holub Marianna Csilla  Kovalszky Ilona  Wade John D  Doll Michelle  Cohen Philip L  Manolios Nicholas  Surmacz Eva
Institution:a Department of Biology, Temple University, Philadelphia, PA 19122, United States
b Peptherx Inc., Audubon, PA 19407, United States
c Section of Rheumatology, Temple University School of Medicine, Philadelphia, PA 19140, United States
d Westmead Clinical School, The University of Sydney, Sydney, New South Wales, Australia
e Department of Rheumatology, Westmead Hospital, University of Sydney, Sydney, New South Wales, Australia
f Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary
g 1st Department of Pathology and Experimental Cancer Research, Semmelweis University Medical School, Budapest, Hungary
h Florey Neurosciences Institutes and Department of Chemistry, University of Melbourne, Parkville, Victoria, Australia
i School of Medicine, Temple University, Philadelphia, PA 19140, United States
j Center for Biotechnology, Temple University, Philadelphia, PA 19122, United States
Abstract:
Keywords:Adjuvant-induced arthritis  Antagonist  Inflammation  K/BxN serum arthritis  Leptin  NF-κB pathway  Peptides
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