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表皮生长因子受体在正常大鼠眼组织中的表达
引用本文:熊新春,杜蜀华,魏厚仁.表皮生长因子受体在正常大鼠眼组织中的表达[J].中国组织化学与细胞化学杂志,1999(1).
作者姓名:熊新春  杜蜀华  魏厚仁
作者单位:同济医科大学附属协和医院眼科,同济医科大学附属同济医院眼科
摘    要:采用免疫组织化学方法观察了表皮生长因子受体在正常大鼠眼组织的表达。结果发现:角膜上皮的深层细胞和角膜缘上皮细胞、部分结膜上皮细胞和结膜下结缔组织内成纤维细胞均强烈表达表皮生长因子受体。结果显示:表皮生长因子受体阳性细胞主要分布于眼表层组织。这些细胞不仅是眼组织损伤后修复、而且是多种手术能否成功和某些疾病形成中起重要作用的细胞

关 键 词:  表皮生长因子受体

THE EXPRESSION OF EPIDERMAL GROWTH FACTOR RECEPTOR IN NORMAL EYE TISSUE OF THE RAT
Xiong Xin chun ,Du Shu hua ,Wei Hou ren.THE EXPRESSION OF EPIDERMAL GROWTH FACTOR RECEPTOR IN NORMAL EYE TISSUE OF THE RAT[J].Chinese Journal of Histochemistry and Cytochemistry,1999(1).
Authors:Xiong Xin chun  Du Shu hua  Wei Hou ren
Institution:Xiong Xin chun 1,Du Shu hua 2,Wei Hou ren 1
Abstract:The expression of epidermal growth factor receptor (EGFR) in normal eye tissue of the rat was observed by means of the immunohistochemical method. The strong exrpression of EGFR was found in the corneal epithelial cells near Bowman's membrane, the epithelial cells of limbus, a part of the conjunctival epithelial cells, the fibroblasts of the conjunctiva and the endothelial cells of small blood vessels in conjunctiva and sclera. The results indicate that these EGFR positive cells mainly distribut in superficial tissues of the eye and may play important roles not only in eye tissue repairment after injury but also in the success of various operations and pathogenesis of some diseases.
Keywords:Eye  \ Epidermal growth factor receptor  
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