| 人肾上腺内肽能神经的超微结构 |
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| 引用本文： | 殷树仪.人肾上腺内肽能神经的超微结构[J].中国组织化学与细胞化学杂志,1994(1). |
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| 作者姓名： | 殷树仪 |
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| 作者单位： | 同济医科大学解剖学教研室 |
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| 摘 要： | 应用抗生蛋白链菌素一生物素一过氧化物酶复合物的免疫电镜技术，在相邻切片中，分别观察人肾上腺内ＮＰＹ、ＶＩＰ、ＳＰ和ＣＧＲＰ免疫反应神经纤维的超微结构和免疫反应物的定位。ＮＰＹ和ＶＩＰ免疫反应物位于小颗粒羹泡和线粒体外膜，部分嗜铬细胞呈ＮＰＹ免疫反应阳性。ＳＰ和ＣＧＲＰ免疫反应物主要定位于大颗粒囊泡内。ＳＰ和ＣＧＲＰ免疫反应轴突与嗜铬细胞形成对称性或非对称性的轴体突轴。测量了这４种肽能神经末梢的直径，从而推测其来源，并讨论了该４种神经肽对人肾上腺的作用。
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| 关 键 词： | 神经肽Y（NPY），血管活性肠多肽（VIP），P物质（SP），降钙素基因相关肽（CGRP），免疫电镜，肾上腺，人 |
AN ULTRASTRUCTURAL STUDY OF PEPTIDERGIC NERVE FIBFRS IN THE HUMAN ADRENAL GLAND |
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| Yin Shuyi, Heym CH.AN ULTRASTRUCTURAL STUDY OF PEPTIDERGIC NERVE FIBFRS IN THE HUMAN ADRENAL GLAND[J].Chinese Journal of Histochemistry and Cytochemistry,1994(1). |
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| Authors: | Yin Shuyi Heym CH |
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| Abstract: | By the use of immune electron microscopy of streptavidin-biotin--peroxidase complex,the ultrastructurse of immunoreactive nerve fibers of neuropeptide Y (NPY), vasoactive intestinal polypeptide (VIP), substance P (SP) and calcitonin gene--related--peptide (CGRP) in human adrenal gland were observed in the adjacent section and their. immunoractive materials were localized. NPY-and VIP-immunoreactivitices were mainly localized in small cored vesicles and in external membrane of mitochondria. Some adrenal chromaffin cell exhibited ilke immunoreactlvlty. SP-and CGRP-like lmmunoreactlve material were locallied In largevesicles. SP-and CGRP-lmmunoreactlve a-cons formed symmetric or asymmetric synapseswith adrenal chrommaffi cells.The diameters of the four peptidergic nerve terminals weremeasured,and their origins were inferred Their functions in thes organ were discusses. |
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| Keywords: | Neuropeptide Y (NPY) Vasoactive intestinal polypeptide (VIP) Substence P(SP) Calcitonin gene-related-peptide (CGRP) Immune electron microscopy Adrenal gland Human |
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