Synthesis and structure-activity relationships of open D-Ring galanthamine analogues |
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| Authors: | Herlem Denyse Martin Marie Thérèse Thal Claude Guillou Catherine |
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| Institution: | Institut de Chimie des Substances Naturelles, C.N.R.S., 91198 Cedex, Gif-sur-Yvette, France., |
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| Abstract: | Open D-ring galanthamine analogues were prepared using ring-opening reactions of the quaternarized urethane or oxazolidine functions and were evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition potency. |
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