| 可调脉宽倍频Nd:YAG激光干预兔耳增生性瘢痕的实验研究 |
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| 引用本文： | 谭军,吴东辉,张刚.可调脉宽倍频Nd:YAG激光干预兔耳增生性瘢痕的实验研究[J].激光生物学报,2009,18(1). |
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| 作者姓名： | 谭军 吴东辉 张刚 |
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| 作者单位： | 湖南师范大学第一附属医院整形激光美容科,湖南,长沙,410005 |
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| 摘 要： | 目的:探讨可调脉宽倍频Nd:YAG激光对兔耳增生性瘢痕的治疗作用.方法:制作兔耳增生性瘢痕模型,术后30天对兔耳增生性瘢痕进行可调脉宽倍频Nd:YAG激光干预,观察兔耳瘢痕大体形态和组织病理改变,并采用免疫组化的方法检测兔耳瘢痕治疗前后血管内皮生长因子(vascular endothelial growth factor,VEGF)的表达情况.结果:可调脉宽倍频Nd:YAG激光干预后,兔耳增生性瘢痕出现明显的萎缩,免疫组化检查VEGF表达减弱.结论:可调脉宽倍频Nd:YAG激光可能通过损伤瘢痕组织内的微血管促进兔耳增生性瘢痕萎缩,对早期增生性瘢痕具有治疗作用.
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| 关 键 词： | 可调脉宽倍频Nd:YAG激光 瘢痕 兔 |
A Experimental Study on Variable Pulse Frequency Doubled Nd:YAG Laser Treatment of Rabbit Ears Hypertrophic Scars |
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| TAN Jun,WU Dong-hui,ZHANG Gang.A Experimental Study on Variable Pulse Frequency Doubled Nd:YAG Laser Treatment of Rabbit Ears Hypertrophic Scars[J].ACTA Laser Biology Sinica,2009,18(1). |
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| Authors: | TAN Jun WU Dong-hui ZHANG Gang |
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| Institution: | Department of Plastic and Laser Cosmetic Surgery;the First Affiliated Hospital of Hunan Normal University;Changsha 410005;Hunan;China |
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| Abstract: | Objective: To explore the treatment effect of variable pulsed frequency doubled Nd:YAG laser on the hypertrophic scars of rabbit ears.Methods: Rabbit ear models of hypertrophic scars were built.On the 30th day after injury,the rabbit ear scars were treated with variable pulsed frequency doubled Nd:YAG Laser,the scars were observed morphologically and histologically.The vascular endothelial growth factor(VEGF) expression was detected with immunohistochemistry.Results: After treatment,the rabbit ear hypertrop... |
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| Keywords: | variable pulsed frequency doubled Nd:YAG Laser scar rabbit |
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