1. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia 2. Pushchino State Institute of Natural Sciences, Pushchino, Moscow Region, 142290, Russia
Abstract:
We investigated the cytotoxicity of the fullerene C60 derivatives. We showed that complexes of C60 fullerene with polyvinylpyrrolidone (m.w. of polyvinylpyrrolidone 10000 and 25000), C60-NO2-proline and C60-alanine had no toxic effect on HEp-2 cells. Sodium salt of polycarboxylic derivative of fullerene C60 exerted a pronounced toxic effect on this cell culture.