Study of cytotoxicity of fullerene C60 derivatives |
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| Authors: | A G Bobylev A D Okuneva L G Bobyleva I S Fadeeva R S Fadeev N N Salmov Z A Podlubnaya |
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| Institution: | 1. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia
2. Pushchino State Institute of Natural Sciences, Pushchino, Moscow Region, 142290, Russia
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| Abstract: | We investigated the cytotoxicity of the fullerene C60 derivatives. We showed that complexes of C60 fullerene with polyvinylpyrrolidone (m.w. of polyvinylpyrrolidone 10000 and 25000), C60-NO2-proline and C60-alanine had no toxic effect on HEp-2 cells. Sodium salt of polycarboxylic derivative of fullerene C60 exerted a pronounced toxic effect on this cell culture. |
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