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Computer simulation of microreentry in the sinoatrial node
Authors:R. A. Syunyaev  R. R. Aliev
Affiliation:1. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia
2. Moscow Institute of Physics and Technology, Dolgoprudnyi, Moscow Region, 141700, Russia
Abstract:We have studied the dynamics of reentry inside the sinoatrial node (SAN). We have found that reentry is unstable at high intercellular conductance. Rotating reentry induces a slow migrating crescent-shaped functional block near the SAN boundary. Abnormal conduction from atrial tissue into the SAN occurs after decay of the reentry. Acetylcholine increases the lifespan of reentry in the SAN.
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