Blood lead level and its relationship to essential elements in preschool children from Nanning,China |
| |
| Institution: | 1. Department of Toxicology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China;2. Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China;3. Maternity and Child Care Health Hospital of Guangxi, Nanning, Guangxi, China;4. Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China;1. A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, 119991 Moscow, Russian Federation;2. I. M. Gubkin Russian State University of Oil and Gas, 119991 Moscow, Russian Federation |
| |
| Abstract: | ObjectiveOur study aimed to assess the distribution of blood lead level and its relationship to essential elements in preschool children in an urban area of China.Design and methodsA total of 6741 children aged 0- to 6-year-old were recruited. Levels of lead, zinc, copper, iron, calcium, and magnesium in whole blood samples were determined using atomic absorption spectrometry.ResultsThe mean blood lead level (BLL) and the prevalence of BLL ≥ 10 μg/dl (5.26 ± 4.08 μg/dl and 6.84%, respectively) increased with age gradually, and there was a gender-difference for blood lead, copper, zinc and iron levels. Compared with the group of children who had BLLs < 5 μg/dl, the groups of 5 ≤ BLLs < 10 μg/dl and 10 ≤ BLLs < 15 μg/dl showed higher blood zinc, iron and magnesium levels, and a lower blood calcium level. A positive correlation of lead with zinc, iron and magnesium, and a negative correlation of lead with calcium were found in the group of children with BLL < 5 μg/dl.ConclusionAge- and gender-differences were found when assessing the BLL and intoxication prevalence in preschool children. Metabolic disorder of essential elements was found even with a low level of lead exposure. |
| |
| Keywords: | Blood lead Essential element Preschool children |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
