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In vivo determination of aluminum,cobalt, chromium,copper, nickel,titanium and vanadium in oral mucosa cells from orthodontic patients with mini-implants by Inductively coupled plasma-mass spectrometry (ICP-MS)
Affiliation:1. Department of Orthodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran;2. Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran;3. Leicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, United Kingdom;4. Department of Medical Bacteriology, Tarbiat Modares University, Tehran, Iran;5. Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran;6. Fellowship in Clinical Laboratory Sciences, BioHealth Lab, Tehran, Iran;1. Division of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA;2. Division of Restorative and Prosthetic dentistry, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA;3. Department of Orthodontics, School of Dentistry, Kyungpook National University, Daegu, South Korea
Abstract:Miniscrews are used as orthodontic anchorage devices in the dentistry clinical practice but the in vivo metallic release from these structures has been not previously investigated. The aim of this study was to determine the content of Al, Co, Cr, Cu, Ni, Ti and V in oral mucosa cells of control subjects, patients under orthodontic treatment and with both, orthodontic treatment and miniscrew, in order to know the contribution of these mini-implants to the total metallic content. ICP-MS measurements revealed the following ascending order: Cr < Ni < Ti < Cu < Al, and Co and V were practically undetected. Significant differences in comparison to the control group were found for Cu in the orthodontic group, and for Ni in both, orthodontic and orthodontic + miniscrew groups. Potential correlations among metallic elements and with some clinical factors were also explored. These findings suggest that miniscrews do not increase significantly the metal release.
Keywords:Metals  Oral mucosa cells  Orthodontic  Miniscrew
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