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Analysis of the AluPolymorphism in the Buryat Populations
Authors:Khitrinskaya  I Yu  Stepanov  V A  Puzyrev  V P
Institution:(1) Institute of Medical Genetics, Tomsk Research Center, Russian Academy of Medical Sciences, Tomsk, 634050, Russia;(2) Tomsk State University, Tomsk, 634050, Russia;(3) Siberian State Medical University, Tomsk, 634050, Russia
Abstract:Polymorphism of three populations of the Buryat Republic and a population from Aginskii Buryat Autonomous okrug of Chita oblast was examined using a set of five autosomal Aluinsertions at theACE, PLAT, PV92, APOA1,and F13Bloci. The allele frequency distribution patterns revealed in Buryat populations were typical to other Asian populations. Buryats were characterized by relatively low level of intrapopulation diversity (0.369 in the pooled population sample). Analysis of autosomal Aluinsertions suggests the uniformity of the Buryat gene pool. The coefficient of genetic differentiation in the four populations studied was 0.8%.
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