Killing cancer cells by targeted drug-carrying phage nanomedicines |
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| Authors: | Hagit Bar Iftach Yacoby Itai Benhar |
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| Institution: | (1) Department of Molecular Microbiology and Biotechnology, The George S. Wise Faculty of Life Sciences, Tel-Aviv University, Ramat Aviv, 69978, Israel;(2) Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, 76100, Israel |
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| Abstract: | Background Systemic administration of chemotherapeutic agents, in addition to its anti-tumor benefits, results in indiscriminate drug
distribution and severe toxicity. This shortcoming may be overcome by targeted drug-carrying platforms that ferry the drug
to the tumor site while limiting exposure to non-target tissues and organs. |
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