Transcending the impenetrable: how proteins come to terms with membranes |
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Authors: | G von Heijne |
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Affiliation: | Department of Molecular Biology, Karolinska Institutet, Huddinge University Hospital, Sweden. |
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Abstract: | In the living cell, proteins are efficiently sorted to a whole range of subcellular compartments. In many cases, sorting specificity is mediated by short 'sorting signals' attached either permanently or transiently to the protein. At long last, a fairly coherent picture of the design and function of many such sorting signals is beginning to emerge. |
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