|
|||||
|
|
Effect of cocarboxylase on hyperlactatemia and hyperpyruvicemia induced by phenformin in dogs] |
|
| Authors: | G Valette G Ribes A M Rondot M M Loubatières-Mariani A L Loubatières |
| Abstract: | In the normal anesthetized dog, a cocarboxylase perfusion considerably reduced the increase in blood lactate and pyruvate levels provoked by the intraduodenal injection of phenformin (30 mg/kg); furthermore it seems to counteract the increase of the lactates/pyruvates ratio and opposes the fall in blood pH. |
| Keywords: | |