| 致病性细菌微进化的研究进展 |
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| 引用本文： | 杨瑞馥. 致病性细菌微进化的研究进展[J]. 生命科学, 2009, 0(4): 479-484 |
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| 作者姓名： | 杨瑞馥 |
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| 作者单位： | 军事医学科学院微生物流行病研究所病原与生物安全国家重点实验室,北京100071 |
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| 基金项目： | 国家重点基础研究发展计划“973”项目（2009CB522604）;国家自然科学基金杰出青年基金项目（30525025） |
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| 摘 要： | 2009年是达尔文诞辰200周年,《物种起源》发表150周年。值此之际,我们将致病性细菌微进化的遗传学动力、研究方法及其意义进行综述,并以鼠疫耶尔森氏菌与沙门氏菌为例讨论了这两种细菌的微进化研究进展。
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| 关 键 词： | 微进化 致病菌 鼠疫耶尔森氏菌 沙门氏菌 |
Advances in microevolution of pathogenic bacteria |
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| YANG Rui-fu. Advances in microevolution of pathogenic bacteria[J]. Chinese Bulletin of Life Sciences, 2009, 0(4): 479-484 |
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| Authors: | YANG Rui-fu |
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| Affiliation: | YANG Rui-fu (Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China) |
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| Abstract: | The year of 2009 is the 200^th anniversary of Charles Darwin＇s birth and the 150^th anniversary of his great book, The Origin of Species. For commemorating Darwin＇s indispensable contribution to evolution, this review focused on bacterial pathogen＇s evolution, including driving forces of genetic changes, the methods of studying bacterial microevolution and the significance of this kind of studies. Yersinia pestis and Salmonella were taken as examples to illustrate their microevolution. |
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| Keywords: | microevolution pathogenic bacteria Yersinia pestis Salmonella |
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