| 血液中氧化三甲胺与相关疾病及检测方法 |
| |
| 引用本文： | 阮亮亮,李金蓉. 血液中氧化三甲胺与相关疾病及检测方法[J]. 生命的化学, 2021, 41(2): 339-343 |
| |
| 作者姓名： | 阮亮亮 李金蓉 |
| |
| 作者单位： | 上海医药临床研究中心,上海200032;上海医药临床研究中心公司,上海200032;上海枫林医药医学检验有限公司,上海200231;上海生物样本库工程技术研究中心,上海200231;上海枫林医药医学检验有限公司,上海200231 |
| |
| 基金项目： | 徐汇枫林生命健康科技成果转化平台项目(枫林HUB)(ZJ2020-ZD-002);上海市重大疾病临床生物样本实体库专业技术服务平台项目(18DZ2294100);生物样本库样本质量控制共性技术标准研究项目(16DZ0500600)。 |
| |
| 摘 要： | 随着代谢组学技术的不断发展及科学研究的不断深入,生物标志物用于预判或诊断机体疾病的价值被更多的科学家所重视.最近几年,大量文献报道了氧化三甲胺与机体疾病之间的相关性.本文通过对近几年血氧化三甲胺与各种疾病之间的关系研究进展及测量方法(如液质联用法、酶联免疫法、磁共振法等)的系统综述,以期为今后的研究提供便捷的参考途径.
|
| 关 键 词： | 氧化三甲胺 心脑血管疾病 测量方法 |
Research progress of TMAO in blood with related diseases and measurement methods |
| |
| RUAN Liangliang,LI Jinrong. Research progress of TMAO in blood with related diseases and measurement methods[J]. Chemistry of Life, 2021, 41(2): 339-343 |
| |
| Authors: | RUAN Liangliang LI Jinrong |
| |
| Affiliation: | (Shanghai Clinical Research Center,Shanghai 200032,China;Shanghai Clinical Research Center Co.Ltd,Shanghai 200032,China;Shanghai Fenglin Clinical Laboratory Co.,Ltd,Shanghai 200231,China;Shanghai Engineering Research Center of Biobank,Shanghai 200231,China) |
| |
| Abstract: | With the continuous development of metabonomics technology and the deepening of scientific research, more and more scientists pay attention to biomarkers in predicting or diagnosing diseases. In recent years, a large number of research reported the correlation between trimethylamine oxide and human diseases. In this paper, the relationship between blood trimethylamine oxide and various diseases and the measurement methods(such as liquid chromatography-mass spectrometry, enzyme-linked immunosorbent assay, nuclear magnetic resonance) were reviewed in order to provide a convenient reference for future research. |
| |
| Keywords: | trimethylamine N-oxide cardiovascular and cerebrovascular diseases measurement method |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
