|
|||||
|
|
Genotoxicity of ptaquiloside, a bracken carcinogen, in the hepatocyte primary culture/DNA-repair test |
|
| Authors: | H Mori S Sugie I Hirono K Yamada H Niwa M Ojika |
| Abstract: | The genotoxicity of ptaquiloside (PT), recently isolated from bracken fern and shown to be carcinogenic, was examined by means of the hepatocyte primary culture/DNA-repair test. PT elicited clear unscheduled DNA synthesis with a dose-response effect. The result indicates that PT is a genotoxic carcinogen. |
| Keywords: | |