Centrosome movement in the early divisions of Caenorhabditis elegans: a cortical site determining centrosome position |
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Authors: | A A Hyman |
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Institution: | Laboratory of Molecular Biology, Medical Research Council, Cambridge, England. |
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Abstract: | In Caenorhabditis elegans embryos, early blastomeres of the P cell lineage divide successively on the same axis. This axis is a consequence of the specific rotational movement of the pair of centrosomes and nucleus (Hyman, A. A., and J. G. White. 1987. J. Cell Biol. 105:2123-2135). A laser has been used to perturb the centrosome movements that determine the pattern of early embryonic divisions. The results support a previously proposed model in which a centrosome rotates towards its correct position by shortening of connections, possibly microtubules, between a centrosome and a defined site on the cortex of the embryo. |
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