New wrinkles and folds in site-specific recombination

The new work of reveals a new site-specific recombination strategy to establish lysogeny, in which a double-stranded recombination substrate is assembled from the folded single-stranded DNA genome of the filamentous Vibrio cholerae phage CTXphi. This strategy allows the phage to use the host's recombinases while at the same time preventing inappropriate excision of the prophage.