The missing linker: an unexpected role for a histone deacetylase |
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| Authors: | Kopito Ron R |
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| Affiliation: | Department of Biological Sciences, Bio-X Program, Stanford University, Stanford, CA 94305, USA. |
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| Abstract: | Molecular motors are the long-haul carriers of eukaryotic cells, moving cargos bidirectionally along microtubule tracks. In the December 12th issue of Cell, report that HDAC6, a tubulin deacetylase, functions as an adaptor that links cargos of aggregated protein to the minus end-directed motor, cytoplasmic dynein. |
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