Asthma,allergy and the risk of prostate cancer: Results from the Montreal PROtEuS study |
| |
Institution: | 1. Epidemiology and Biostatistics Unit, INRS-Institut Armand-Frappier, Institut national de la recherche scientifique, Université du Québec, Laval, Québec, Canada;2. University of Montreal Hospital Research Centre (CRCHUM), Montréal, Québec, Canada;3. School of Public Health, Department of Social and Preventive Medicine, Université de Montréal, Montréal, Québec, Canada;1. Department of Animal Science, Iowa State University, Ames, IA 50011, USA;2. Department of Physiology, University of Arizona, Tucson, AZ 85724, USA;3. INRS—Institut Armand-Frappier Research Centre, University of Quebec, Laval, QC H7V 1B7, Canada |
| |
Abstract: | BackgroundThe few previous studies examining the association between asthma or allergy and prostate cancer (PCa) risk were inconclusive. This study aimed to evaluate these associations, and to explore in details the possible influence of current versus former allergic condition, age at onset, time since onset, and duration of each allergic condition.MethodsDetailed information on self-reported asthma and allergy was collected in the context of a large population-based case–control study conducted in Montreal, Canada. Study subjects included 1936 cases, diagnosed between 2005 and 2009, and 1995 population controls. Unconditional multivariate logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) adjusting for age, ancestry and familial history of prostate cancer.ResultsThe ORs were 1.11 (95% CI: 0.89–1.40) and 0.98 (95% CI: 0.84–1.14) for ever reporting of asthma and allergy, respectively. These ORs did not substantially vary according to status (former or current), age at onset, time since onset, and duration of each allergic condition. PCa screening was not associated with allergic diseases reporting.ConclusionsOverall, our findings are in line with the absence of an association between a history of asthma or allergy, and PCa risk. |
| |
Keywords: | Prostate cancer Asthma Allergy Hay fever Case–control study |
本文献已被 ScienceDirect 等数据库收录! |
|