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Comparative Study of Liver Cancer Patients in Arsenic Exposed and Non-exposed Areas of Pakistan
Authors:Sham Kumar Wadhwa  Tasneem Gul Kazi  Akhtar Ali Chandio  Hassan Imran Afridi  Nida Fatima Kolachi  Sumaira Khan  Ghulam Abbas Kandhro  Syeda Nasreen  Abdul Qadir Shah  Jameel Ahmed Baig
Institution:National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, 76080, Pakistan. wadhwashamkumar@yahoo.com
Abstract:The investigated data shows that arsenic (As) in drinking water is associated with increased mortality from different types of cancers including liver cancer. In this study, blood and scalp hair samples of male liver cancer patients and healthy referents belonging to As exposed areas of Sindh Pakistan were analyzed for As contents. The As levels in drinking water of understudy area showed that sections of this population was exposed to 3-15-folds higher concentrations of As than permissible limit. For comparative purposes, blood and scalp hair samples of matched cancerous patient as referent patients belonging to big city (Hyderabad) who have used municipal treated water with low As levels <10?μg/L were also collected. The results of this study showed that the average As concentration was higher in the blood and scalp hair of exposed and non-exposed referent cancer patients as compared to referents (p?
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