| 手性技术与生物催化 |
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| 引用本文： | 孙志浩. 手性技术与生物催化[J]. 生物加工过程, 2004, 2(4): 6-10,16 |
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| 作者姓名： | 孙志浩 |
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| 作者单位： | 江南大学,生物工程学院,无锡,214036 |
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| 基金项目： | 973项目课题 (2 0 0 3CB7160 0 8)，国家自然科学基金项目 (2 0 4760 3 9)资助 |
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| 摘 要： | 简要介绍了手性，手性技术与生物催化的基本概念。手性，是指一个有机分子具有不对称性，形成两种空间排布方式不同的对映异构体。手性技术即生产手性化合物的技术，手性化合物的制备方法主要有手性源、外消旋体拆分、不对称合成等几种。生物催化，即利用酶或微生物等生物材料催化进行某种化学反应，被认为是手性化合物生产取得突破的关健技术。文章还介绍了生物催化外消旋体拆分、生物催化不对称合成等几种生产手性化合物的应用实例。
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| 关 键 词： | 手性 手性技术 生物催化 外消旋体拆分 不对称合成 |
| 文章编号： | 1672-3678(2004)04-0006-05 |
| 修稿时间： | 2004-07-03 |
Chirotechnology and biocatalysis |
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| SUN Zhi hao. Chirotechnology and biocatalysis[J]. Chinese Journal of Bioprocess Engineering, 2004, 2(4): 6-10,16 |
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| Authors: | SUN Zhi hao |
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| Abstract: | In this review,simply basic concepts about chirality,chirotechnology and biocatalysis were introduced Chirality means that one organic molecule possesses dissymmetry and thus forms two enantiomers with different stereo structures Chirotechnology refers to the preparation of chiral compounds by some means mainly including chiral source, racemic resolution, asymmetric synthesis and so on Biocatalysis means that enzymes or microbes are utilized to catalyze chemical reactions, and it is a key technology to produce chiral compounds This paper also introduced some practical examples producing chiral compounds by racemic resulution or dissymmetry synthesis |
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| Keywords: | chirality chirotechnology biocatalysis racemic resolution asymmetric synthesis |
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