Comparative tissue morphology in using prostheses from polypropylene and polytetrafluoretilen

To treat hernias, polymer net implants are widely used. We carried out a comparative study of the morphological picture of inflammation, cellular composition of tissues, and dynamics of scar formation in mice in using the implants Esfil and Uniflex under conditions of single and double introduction of cultivated fibroblasts and without fibroblasts in the area of disposition of the endoprostheses. A more expressed inflammatory reaction throughout the entire period of time was observed in implantation of the material Esfil. In using the material Uniflex, there was revealed a higher percent of fibroblasts than in using the Esfil prosthesis. Introduction of cultivated fibroblasts in using both materials modified the curve of dynamics of the inflammatory process by making it smoother. Use of the Uniflex endoprosthesis is preferable.