Design and an efficient synthesis of natural product-based cyclopenta[b]pyran derivatives with potential bioactivity |
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| Authors: | Yao Changsheng Jiang Bei Li Tuanjie Qin Bingbin Feng Xiaodong Zhang Honghong Wang Cuihua Tu Shujiang |
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| Institution: | School of Chemistry and Chemical Engineering, Xuzhou Normal University, Key Laboratory of Biotechnology for Medicinal Plant, Xuzhou, Jiangsu 221116, PR China. |
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| Abstract: | A series of 4-aryl-cyclopentab]pyran derivatives, designed based on natural product scaffold, were synthesized efficiently via multi-component reaction under solvent-free and catalyst-free conditions. This chemistry provides a new compound library with potential activity for biomedical screening. |
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