DNA-BAR: distinguisher selection for DNA barcoding |
| |
| Authors: | DasGupta B Konwar K M Mandoiu I I Shvartsman A A |
| |
| Affiliation: | Department of Computer Science, University of Illinois at Chicago, Chicago, IL 60607-7053, USA. |
| |
| Abstract: | DNA-BAR is a software package for selecting DNA probes (henceforth referred to as distinguishers) that can be used in genomic-based identification of microorganisms. Given the genomic sequences of the microorganisms, DNA-BAR finds a near-minimum number of distinguishers yielding a distinct hybridization pattern for each microorganism. Selected distinguishers satisfy user specified bounds on length, melting temperature and GC content, as well as redundancy and cross-hybridization constraints. |
| |
| Keywords: | |
| 本文献已被 PubMed Oxford 等数据库收录！ |
|
