A novel liver specific isoform of the rat LAR transcript is expressed as a truncated isoform encoded from a 5'UTR located within intron 11 |
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| Authors: | Simon JM Welham Adrian JL Clark Andrew M Salter |
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| Affiliation: | (1) Division of Nutritional Sciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, LE12 5RD, UK;(2) Centre for Endocrinology, Barts & the London, Queen Mary University of London, UK |
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| Abstract: | Background The leukocyte common antigen related receptor (LAR) protein has been shown to modulate the signal transduction of a number of different growth factors, including insulin and insulin-like growth factor 1. Splice variants exhibit differing roles and are expressed according to tissue type and developmental stage. |
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