The complement system |
| |
Authors: | J Vidya Sarma Peter A Ward |
| |
Institution: | (1) Department of Pathology, The University of Michigan Medical School, 1301 Catherine Rd., Box 5602, Ann Arbor, MI 48109-5602, USA; |
| |
Abstract: | The complement system consists of a tightly regulated network of proteins that play an important role in host defense and
inflammation. Complement activation results in opsonization of pathogens and their removal by phagocytes, as well as cell
lysis. Inappropriate complement activation and complement deficiencies are the underlying cause of the pathophysiology of
many diseases such as systemic lupus erythematosus and asthma. This review represents an overview of the complement system
in an effort to understand the beneficial as well as harmful roles it plays during inflammatory responses. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|