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Lipoxins: study of various biosynthesis pathways |
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| Authors: | G F Sud'ina O K Mirzoeva I A Shchukin V E Shevchenko R S Vorisova G I Miagkova S D Varfolomeev |
| Abstract: | Lipoxins A4 and B4 were obtained by using soybean lipoxygenase and blood cells as a source of enzymatic activity. The conditions facilitating lipoxin biosynthesis from arachidonic acid catalyzed by soybean 15-lipoxygenase were selected. A comparative analysis of lipoxin biosynthesis with the use of cell suspensions containing only granulocytes and of mixed suspensions (platelets + granulocytes and platelets + total fraction of blood leucocytes) was carried out. |
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