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A novel Bxb1 integrase RMCE system for high fidelity site‐specific integration of mAb expression cassette in CHO Cells |
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| Authors: | Mara C Inniss Kalpanie Bandara Barbara Jusiak Timothy K Lu Ron Weiss Liliana Wroblewska Lin Zhang |
| Institution: | 1. Cell Line Development, Biotherapeutics Pharmaceutical Science, Pfizer Inc, Andover 01810, Massachusetts;2. Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts;3. BioMedicine Design, Pfizer Inc, Cambridge, Massachusetts;4. 9782471406845‐474‐5751 |
| Abstract: | |
| Keywords: | CRISPR RMCE site‐specific integration monoclonal antibody cell line development |