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Peptide mass fingerprinting using isotopically encoded photo-crosslinking amino acids
Authors:Wilkins Bryan J  Daggett Kelly A  Cropp T Ashton
Institution:Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Abstract:When isotopically labelled photo-crosslinking amino acids are site-specifically incorporated into proteins, in combination with the corresponding non-labeled analogue, cross-linked tryptic peptides are easily identified in mass spectra via characteristic "doublet" patterns.
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