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Novel TIE‐2 inhibitor BAY‐826 displays in vivo efficacy in experimental syngeneic murine glioma models
Authors:Hannah Schneider  Emese Szabo  Raquel A. C. Machado  Angela Broggini‐Tenzer  Alexander Walter  Mario Lobell  Dieter Heldmann  Frank Süssmeier  Sylvia Grünewald  Michael Weller
Affiliation:1. Laboratory of Molecular Neuro‐Oncology, Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland;2. Laboratory for Molecular Radiobiology, Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland;3. GTRG Oncology II, Drug Discovery, Bayer Pharma AG, Berlin, Germany;4. Medicinal Chemistry, Drug Discovery, Bayer Pharma AG, Wuppertal, Germany;5. Center for Neuroscience, University of Zurich, Zurich, Switzerland
Abstract:
Keywords:BAY‐826  glioma  irradiation  syngeneic  TIE‐2 inhibition
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