cis-1,4-diaminocyclohexane-Pt(II) and -(IV) adducts with DNA bases and nucleosides |
| |
| Authors: | Ali Mohammad S Khokhar Abdul R |
| |
| Institution: | Department of Experimental Therapeutics, Box 353, The University of Texas, M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. |
| |
| Abstract: | A series of new platinum(II) and platinum(IV) adducts of type P(II)(cis-1,4-DACH)LCl]NO(3,) where cis-1,4-DACH=cis-1,4-diaminocyclohexane, and L=9-ethylguanine, 1-methylcytosine, adenine, adenosine, cytosine, cytidine, guanine, and Pt(IV)(cis-1,4-DACH)Ltrans-(X)(2)Cl]NO(3), (where Y=hydroxo or acetato), were synthesized and characterized by elemental analysis, infrared spectroscopy, and 1H and 195Pt nuclear magnetic resonance spectroscopy. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
