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Nature of the change in cytostatic and cytotoxic splenocyte functions in mice after immobilization stress
Authors:G T Sukhikh  I V Bogdashin  L V Van'ko
Abstract:It has been shown that at late periods after immobilization stress there is an essential reduction in the cytostatic activity of CBA mice splenocytes detected by inhibition of mastocytoma P 815 cell proliferation in the test with 3H-uridine incorporation. The cytostatic activity returns to normal 5 to 14 days after stress. The changes in the cytolytic and cytostatic activity of mouse splenocytes following stress are correlated and a possible biological value of changes in the immunoassays for the host are discussed.
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