Hepatitis E: an overview |
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| Authors: | Worm Harald C van der Poel Wim H M Brandstätter Gerald |
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| Affiliation: | 1. Second Department of Medicine, Department of Gastroenterology and Hepatology, LKH-Universitätsklinikum Graz, Auenbruggerplatz 15, A-8036 Graz, Austria;2. Microbiological Laboratory for Health Protection, National Institute of Public Health and the Environment (RIVM), P.O. box 1, Antonie van Leeuwenhoeklaan 9, 3720 BA Bilthoven, Netherlands |
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| Abstract: | The hepatitis E virus (HEV) is a non-enveloped, positive-sense, single-stranded RNA virus with icosahedral symmetry. Although it is related to the alpha-virus superfamily, the HEV is classified as a separate Hepatitis E-like viruses genus. Infection in humans occurs in sporadic and epidemic forms and can cause an acute, self-limited, icteric hepatitis. Recent studies indicate the existence of a reservoir in animals. |
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